This paper utilizes ideas from biological life to examine the architectural condition in which we live. We reveal how modern-day designs have come to operate in exclusion of any connection between the built environment and the primary animating properties of living structure, i.e. (i) organized-complexity, (ii) metabolism, (iii) replication, (iv) adaptation, (v) intervention, (vi) situatedness, and (vii) connectivity. Architecture today for the most part seems empty and lifeless, devoid of the requisite innate information necessary to engage sentient human beings in their everyday lives. Unintelligible in its form and application, architecture as a built form no longer carries with it the power to affect the lived experience. Drawing analogies from living structure and artificial intelligence, we find the promise of a new direction for architecture in the 21st century. Looking to modern robotic science and technology, a strong correlation can be made between biologically-driven functions of living structure and the adaptive processes that once gave form to architecture, and which now serve to steer the Mars Explorer.